چكيده به لاتين
In this work, three-component Mannich reaction between 2-hydroxy-1,4-naphtoquinone,
aromatic aldehydes and amines in the presence of carboxymethyl celloulose (CMC) as a
catalyst and by using ball-mill for synthesis of 3-aminoalkyl-2-hydroxy-1,4-naphtoquinone
were performed. CMC can be recoverd easily and reused without any appreciable loss of
catalytic activity. The advantages of this procedure are mild and solvent-free conditions, short reaction time, high yields, safety, easy separation of the catalyst and non-toxic inexpensive
catalyst.
Keywords:
Three-component Mannich reaction, ¬2-hydroxy-1,4-naphtoquinone, solvent free, ball-mill, carboxymethyl celloulose.