چكيده به لاتين
Pharmaceutical pollutants are considered one of the acute problems in modern life. Login drugs including active components (PhACs) analgesics, antibiotics, disinfectants and hormones to the food cycle lead to many environmental hazards. Hence finding a suitable method for the isolation of drugs from water, is vital and important. In recent years the use of membrane processes, especially emulsion liquid membrane to separate chemical elements have been widely used. In the present work the extraction and recovery of diclofenac ions from aqueous solutions using emulsion liquid membrane (ELM) based on response surface experimental design method was studied. Tetra-butyl ammonium bromide (TBAB) as extractant, dichloromethane as a solvent, Span 80 as a surfactant and sodium hydroxide as internal phase have been used. The effect of various factors on the rate of extraction such as feed concentration, carrier concentration, surfactant concentration, the concentration of internal phase, stirring speed, homogenizer speed, the ratio of external phase-to-phase emulsion, the proportion of internal phase-to-phase membranes were studied and optimized. Also the diclofenac ion recovery was investigated under optimum conditions. After conducting tests, the specific function of the behavior of the main variables was obtained by the extraction process. The results showed that the initial concentration of feed, carrier concentration, stirring rate, internal phase concentration, speed homogenizer and the ratio of internal phase-to-phase membranes have the greatest impact on the extraction of ions diclofenac. The best operating conditions of ELM process with the approach of increasing the percentage of diclofenac ion separation were obtained in feed concentration 88 ppm, carrier concentration 0.04 M, surfactant concentration 2% V/V, stirring speed 256 rpm, ratio of external phase volume to emulsion 2.3:1, internal phase concentration 0.16 M, homogenizer speed 6970 rpm and ratio of internal phase volume to phase membrane of 1: 1. In this conditions, percent of extraction and recovery of diclofenac 99.6 and 80% were measured.
