چكيده به لاتين
Despite the poor mechanical properties of hydroxyapatite, its unique biological properties leads to study on improving its properties rather than completely replacing it with other biomaterials. Accordingly, in this study the effect of adding Nitinol as a reinforcement with various percentages to matrix hydroxyapatite was evaluated as a novel bio-nanocomposite.
Nitinol is an intermetallic compound with excellent mechanical properties and good biocompatibility. These features makes this alloy as a excellent alloy for bone implant application. Unfortunately, a few studies had been done about the effect of Nitinol on the mechanical properties of hydroxyapatite.
In this study, porous hydroxyapatite nanocomposite reinforced with 5, 10 and 15 Wt% Nitinol was produced by powder metallurgy successfully. In order to examine changes occurring in the composite phase after sintering and fracture surface, XRD, FTIR and SEM were used, Respectively. Also, porosity and the compressive strength were measured in the purpose comparing the bone properties. In order to evaluate the biocompatibility of produced composite MTT assay, ALP enzyme and cell adhesion were conducted.
Mechanical properties of produced porous nanocomposites showed that the by adding 10% Nitinol, compressive strength of nanocomposite with 30% porosity was increased from 46 MPa in pure hydroxyapatite to 67.67 MPa and compressive strength. of nanocomposite with 50% porosity was increased from 5.67 MPa to 10.33 MPa. Scaning Electron microscope images of the fracture surfaces and crack path, proved that by deviation crack by Nitinol particles the strength increased. According to cell research, nontoxicity and cell attachment suitable samples confirmed the biocompatibility of nanocomposites. It can be concluded that the nanocomposite scaffolds with 10 Wt% of Nitinol has optimal mechanical properties and biological, can be used as a good alternative for orthopedic applications.
