چكيده به لاتين
Nowadays, the synthesis of spinel ferrite nanoparticles with high crystallinity and purity and monodisperse particles with a certain shape and optimum magnetic properties that are used in many medical fields, such as cancer treatment, is one of the research subjects of the researchers. Adherence to the physiological conditions of the body and the lack of toxicity of these particles, together with a reduction in the consumption of these materials along with their increased efficiency, can have an effective role in the application rate of these particles for in-vitro applications. In this study, cobalt ferrite and magnesium ferrite nanoparticles were synthesized by thermal decomposition without solvent at 300 °C. The thermal decomposition conditions were studied in the presence of solvent, the ratio of the precursor to surfactant, temperature, and the reaction time, and the optimal mode was performed after analyzing X-ray diffraction pattern (XRD), Fourier transformation spectroscopy (FTIR), scanning electron microscopy (FE-SEM) and Transmission electrom microscopy (TEM) and Magnetometer Vibration Sample (VSM). Cobalt ferrite nanoparticles were synthesized in the absence of a solvent with a precursor to surfactant 1 to 3 ratio at 300 °C and 30 minute, with the amount of saturation magnetization and the coercivity field obtained 75 emu/g and 870 Oe respectively. Cubic magnesium magnesium ferrite nanoparticles were synthesized at 300 °C and 60 minutes with a magnetization of 24 emu/g and a coercivity 65 Oe. Also, cobalt ferrite nanoparticles were synthesized by low temperature coprecipitation and without extra heat treatment. In these samples, the synthesis temperature and the rate of addition of the precesors to the alkaline medium and the effect of the presence of oleic acid surfactant were investigated. Finally, at 80°C and the presence of oleic acid surfactant, the amount of saturated magnetization and coercivity field were 37 emu/g and 300 Oe, respectively. An increase in the temperature of the hyperthermia test of the cobalt ferrite sample prepared in the same way coprecipitation and thermal decomposition were respectively 7 °C and 14.4 °C, respectively, and in the optimal sample magnesium ferrite synthesized by thermal decomposition was 8 °C.
In order to study the behavior of these two materials in nanocomposite and increase the efficiency, magnesium ferrite nanoparticles were coated on cobalt ferrite nanoparticles prepared by coprecipitation and thermal decomposition, which showed increased the temperature of 18 °C and 6.2 °C in the hyperthermia test, respectively.
