چكيده به لاتين
Magnetic nanoparticles have many applications, some of which are utilized in medical fields. For instance, drug delivery to desired tissue procedures and elimination of cancer tissues by heat. Hyperthermia is one of the cancer tumors treatment methods in which the cancer tissues, which are more sensitive than regular cells to heat, be heated and removed. In magnetic hyperthermia, the magnetic nanoparticles are used for heating cancer tissues. When alternative magnetic field is applied, the nanoparticles start to warm up and then cancer tissues are eliminated.
In this thesis, at first the nanoparticles of magnesium-cobalt ferrite([Mn1-xCoxFe2O4 (0≤x≤0.5)] are synthesized using co-precipitation and then thermal decomposition methods. These nanoparticles are synthesized by thermal decomposition method in presence of polyol, as a solvent, without any surfactants in 280 ºC. For the nanoparticles obtained by both methods, to investigate Co2+ influence on Cation distribution in tetrahedron and octahedron places in spinel structure, study of morphology magnetic properties and characteristics of heat production in alternative magnetic fields, we carry out some analysis such as X-ray diffraction XRD, FE-SEM, TEM, RMAN, FT-IR, VSM and hyperthermia test.
In case of samples synthesized with co-precipitation method, when amount of x increases up to 0.5, the amount of Mr increases continuously, and after it reaches its maximum amount in x = 0.3, it starts to decrease .The size of the nanoparticles in this method was 60 to 110 nm. For mn-co ferrite samples, the increase in temperature resulted from heat therapy test were equal to 4 and 8 when x = 0 and x = 0.3 in 3600 seconds respectively. Then, the thermal decomposition method is applied to decrease in size of particles and to achieve the hydrophobia mn-co nanoparticles. The amount of Mr in this method was very low and the sample of MnFe2O4 (41 emu/g) experienced the maximum of saturation magnetization. The nanoparticles size that produced by this method were lower than 20nm.
