چكيده به لاتين
Ceramic Bredigite ( 〖〖ca〗_7 mgsi〗_4 o_16 ,Br،(is a promising bioactive material for bone tissue engineering, especially in repairing bone defects. However, the low hardness and mechanical strength of Bredigite limits its use in loading and use conditions. Recent findings suggest a promising biocompatibility of graphene, which can be used as an additive to improve mechanical properties. And used the bio of composites. In this study, graphene was synthesized in the presence of bovine albumin protein by Hammers and Bridgetite by sol-gel method. Adding graphene to the elastic modulus of brevity significantly improved the stiffness and toughness of its failure. Graphene in three weight ratios of 5%, 1 and 2% was mixed with bradycetes by physical mixing method. Various hardening mechanisms have been observed, such as bridging the gaps and cracks and leaving the graphene oxide out, thus increasing the crack propagation resistance and leading to improvements in fracture toughness. X-ray diffraction (XRD), electron microscopy (SEM) and field emission electron microscopy (FESEM), transit electron microscopy (TEM), Raman spectroscopy, and FTIR spectroscopy (FTIR) spectroscopy. And morphology and structure of nanopowder and nanocomposites were used. Simultaneous thermal analysis (STA) was used to measure thermal weight (TGA) and differential heat (DTA) to analyze the thermal conductivity of Bredigite. Dynamic light scattering (DLS) analysis was used to distribute the particle size and particle size, and Zeta potential analysis was used to stabilize the graphene and bradygite solution. The biocompatibility of graphene oxide nanocomposite using cellular test methods, methyl thiazol tetrazolium (MTT) in laboratory conditions, showed that bone cell growth and proliferation were significantly increased. The results of cell adhesion showed that the G 292 osteoblasts (bone) cells could adhere to and develop in the bradycardia nanocomposite graphene oxide. In addition, the rate of cell proliferation and activity of alkaline phosphatase (ALP) in the nanocomposite bradygite / graphene oxide has improved compared to the pure ceramic of bradygite. These results suggest that nanocomposite briquette / graphene oxide is a promising material for medical applications.
