چكيده به لاتين
The management of the blood supply chain and its products faces complex challenges due to the unique characteristics of blood, including the uncertainty of the number of donors and patients and the perishability of blood products. For this purpose in this study, a mixed nonlinear planning model is presented by using inventory concepts in order to managing platelet inventory in blood centers and hospitals and locating collection facilities to reduce platelet supply chain costs. In the proposed model, by using the inventory relations, the major platelet inventory is kept in the blood center at each period in order to meet the demand of more hospitals with proper allocation and also to prevent platelet perishability due to having proper storage conditions. Meanwhile, blood centers keep a number of platelets in their blood bank as a safety stock to meet emergency demands. After platelet production, in order to make the best use of the produced platelets, the FIFO policy has been used in allocating platelets to hospitals and patients which increases the freshness of produced platelets and reduces the number of wastage units in blood centers and hospitals. The mathematical model has been approximated into a linear programming model using the piecewise linearization method and then has been solved with the GAMS software. The results show that by using the proposed model, considering the mobile collection facilities and the coverage radius, the number of donors increases, which increases the number of produced platelets. On the other hand, by using the concepts of inventory, the amount of inventory in blood centers can be determined in such a way that in addition to optimal allocation of platelets to hospitals, which reduces platelet shortage in hospitals, by reducing inventory holding in hospitals, the amount of wastage in blood centers and hospitals will also be significantly reduced.
