eva‎luation and comparison of antibacterial and photoxidation properties of porphyrin-modified titanium dioxide nanoparticles in anatase and rutile phases

4/20/2023 12:00:00 AM

In this project, tetra-carboxyphenyl porphyrin (TCPP) was first synthesized by the Adler method. Then titanium dioxide (TiO2) nanoparticles in two phases naming anatase and rutile were modified by porphyrin (TCPP) by reflux method and modified nanoparticles were eva‎luated and characterized using Fourier-transform infrared spectroscopy (FT-IR), electron microscopy imaging field emission scanning (FE-SEM), X-ray diffraction pattern (XRD), X-ray energy diffraction (EDS), reflectance spectroscopy (DRS) and zeta potential analyzer. The modified nanoparticles effectively produced reactive oxygen species (ROS) under the LED light. Subsequently, the antimicrobial performance of porphyrin-modified nanoparticles against Gram-negative Escherichia coli was further investigated. Data show a relative reduction in bacterial viability after photodynamic inactivation (PDI) by titanium dioxide nanoparticles. The results showed that porphyrin (TCPP) modified titanium dioxide (TiO2) based materials are effective photocatalysts that can be used successfully in biomedical strategies, especially photodynamic inactivation of microorganisms

نانو ذرات تيتانيوم دي اكسيد، پورفيرين، غير فعال سازي فوتوديناميكي ميكروارگانيسم¬ها، گونه¬هاي فعال اكسيژن، باكتري اشريشياكلي

Titanium dioxide, Porphyrin, Photodynamic inactivation of microorganisms, Oxygen active species, Escherichia coli bacteria

Zahra Moradi Nasab

Prof. Rahmatollah Rahimi