چكيده به لاتين
In this study, a new heterogeneous magnetic catalytic system based on diselenide bond (Se-Se) is presented and suggested for facile formation of amide/peptide bonds. Firstly, the prepared nanocatalyst, formulated as “Fe3O4/SiO2-DSBA” (DSBA stands for 2,2'-diselanediylbis benzamide), has been precisely characterized for identifying its physicochemical properties. For this purpose, Fourier-transform infrared (FTIR), energy-dispersive X-ray spectroscopy (EDX), electron microscopy, Vibrating-sample magnetometer (VSM), Mass spectroscopy, and Nuclear Magnetic Resonance (NMR) were utilized. As the most significant advantage of the designed catalytic system its high efficiency can be referred, where only a small amount of Fe3O4/SiO2-DSBA has resulted in ca. 89% reaction yield in the catalyzed synthesis of the amide bonds between the amino acids, under a mild condition. Also, given the growing importance of the green chemistry in all scopes of the science, easy separation of the Fe3O4/SiO2-DSBA particles from the reaction medium through its super-paramagnetic property (ca. 30 emu·g-1) should be noticed. Another advantage of the Fe3O4/SiO2-DSBA nanocatalyst is its capability to be recovered and reused several times, where after five successive cycles ca. 67% efficiency has been obtained. Moreover, due to showing other brilliant excellences such as economic benefits, nontoxicity, convenient preparation, and etc., the presented catalytic system is recommended to be scaled up and exploited in the industrial applications.
