28154

ﺳﻧﺗز ﮐﺎﺗﺎﻟﯾزور ﻣﻐﻧﺎطﯾﺳﯽ MnFe2O4@SiO2@Histidine-Ag و ﺑررﺳﯽ آن در ﺳﻧﺗز ﻣﺷﺗﻘﺎت tetrazolo[1,5-α]pyrimidines

كارشناسي ارشد

شيمي آلي

1396

1400/02/18

محمدرضا نعيمي جمال

شيمي

ﮐﺎﺗﺎﻟﯿﺰور زﯾﺴﺘﯽ ﻣﻐﻨﺎﻃﯿﺴﯽ ﺑﺮ ﭘﺎﯾﻪ ﻫﯿﺴﺘﯿﺪﯾﻦ ﮐﻪ ﯾﮏ اﺳﯿﺪ آﻣﯿﻨﻪ ﺿﺮوري و ﻣﻬﻢ در ﻓﺮآﯾﻨﺪ ﻣﺘﺎﺑﻮﻟﯿﮑﯽ ﺳﺎﺧﺖ ﭘﺮوﺗﺌﯿﻦ ﻣﯿﺒﺎﺷﺪ ﺗﻬﯿﻪ ﮔﺮدﯾﺪ و ﺑﻪ ﮐﻤﮏ آﻧﺎﻟﯿﺰﻫﺎيFT-IR ، ﻣﯿﮑﺮوﺳﮑﻮپ اﻟﮑﺘﺮوﻧﯽ روﺑﺸﯽ )SEM( و آﻧﺎﻟﯿﺰ ﺗﻔﺮق ﭘﺮﺗﻮ اﯾﮑﺲ ﺷﻨﺎﺳﺎﯾﯽ ﺷﺪ.MnFe2O4@SiO2@Histidine-Ag ﺑﻪ ﻋﻨﻮان ﮐ ﺎﺗﺎﻟﯿﺰﮔﺮي ﭘﺎﯾﺪار و ﻣﻮﻓﻖ در ﺳﻨﺘﺰ ﺗﮏ ﻇﺮف ﺳﻪ ﺟﺰﯾﯽ ﻣﺸﺘﻘﺎت tetrzolo[1,5-α]pyrimidines از ﻃﺮﯾﻖ واﮐﻨﺶ ﺑﯿﻦ اﺗﯿﻞ اﺳﺘﻮاﺳﺘﺎت ، 5-آﻣﯿﻨﻮﺗﺘﺮازول و ﺑﻨﺰآﻟﺪﻫﯿﺪ ﺗﺤﺖ ﺷﺮاﯾﻂ رﻓﻼﮐﺲ و ﺣﻼل اﺗﺎﻧﻮل، در زﻣﺎن ﮐﻢ و ﺑﺎزده ﺑﺎﻻ اﺳﺘﻔﺎده ﺷﺪ

1402/02/04

Synthesis of magnetic catalyst MnFe2O4 @ SiO2 @ Histidine-Ag and its study in the synthesis of tetrazolo [1,5-α] pyrimidines

5/8/2022 12:00:00 AM

Magnetic biocatalyst based on histidine, which is an essential amino acid in the metabolic process of protein production, was prepared and identified by FT-IR analysis, scanning electron microscopy SEM and XRD scattering analysis. MnFe2O4 @ SiO2 @ Histidine-Ag as a stable and successful catalyst in the synthesis of single-component three-component tetrzolo [1,5-α] pyrimidines derivatives through the reaction between ethyl acetoacetate, 5-aminotetrazole and aromatic aldehyde under reflux and ethanol solvent , Used in low time and high efficiency.

Maryam Azad

Mohamadreza Naimi Jamal