پري زارع نعمتي

In the present study، we tried to creat a porous structure of Ti6Al 4V titanium alloy by powder metallurgy. First, turning the scrapto the powder and then pressing them,the cylinders with a diameter of 3 mm and a height of 30 mm and with different porosity percentage shold be prepared.The purpose of this project is to investigate the effect of porosity in the sample on the penetration and growth of the body tissue so that the degree of compatibility between the implant and the bone can be eva‎luated. The long-term stabilization of an implant requires comprehensive studies that have been addressed as much as possible in this research. To produce porosity, magnesium powder particles were used as a necessary spacer and after mixing the desired percentages of sample powder and spacer. , under cold isostatic pressure with a pressure of 450 Mpa and in a silicone mold, it was sintered at 1200 ℃ for 6 hours. The study methods of XRD electron diffraction, SEM and EDS analysis were used for phase and elemental study.By cutting from the surface and length of the samples and their metallography, the microstructures were studied and photographed. Clemxe software was used to check the percentage of residual porosity.In order to compare the effect of composite coating of hydroxyapatite (HA) and titanium dioxide 〖TiO〗_2, the electrophoretic coating method was used and the best deposit was obtained by obtaining a stable phase of 65%wt HA and 35%wt Tio_2.The results obtained from the cell adhesion test indicated the proper adhesion of the cells to the samples, and the results of the SBF test and the MTT cytotoxicity test also showed an increase in the viability of coated samples compared to uncoated samples.

پوشش Tio2/HA , پوشش الكتروفورز Ti6Al 4V پودري , چسبندگي سلولي , مايع شبيه سازي بدن , آزمايش سميت سلولي سميت سلولي MTT

Tio2/HA coating , powder electrophoresis Ti6Al 4Vcoating , cell adhesion , SBF , MTT cytotoxicity test

Zeinab Gheitasi

Dr. Morteza Tamizifar