چكيده به لاتين
Due to their simplicity of production, low cost, high detection accuracy, fast detection speed, and ability to be manufactured in tiny quantities, electrochemical biosensors have become one of the best sensors. A common example is the biosensor for detecting blood sugar, whose function is to detect the concentration of glucose in the blood. In this study, a sample of these electrochemical biosensors that is simple, inexpensive, and accurate has been explored. This study begins with the creation of a suitable substrate for the biological component whose responsibility is to detect the studied component. This substrate was chosen and manufactured owing to its exceptional qualities, such as its high surface energy, porosity, and several others, which will be explained in further detail below. This substrate is composed of graphene oxide and metal-organic framework (MOF). Next, this biological component, which in this investigation is the protein Trastuzumab or Herceptin, is deposited on the substrate and electrode. Then, the surface of the electrode, which now contains a biological component, is brought into contact with the examined component, which is the HER2+; breast cancer cell SK-BR-3, to fulfill its function. According to the findings of the inquiry, the identification process was straightforward, highly accurate, and error-free.
