حسين صالحي واناني

In this research, a novel heterogeneous magnetic catalyst based on metal- organic framework was made to be used in the synthesis reaction of amide compounds. In this regard, magnetic nanoparticles of iron oxide were synthesized and then covered with a layer of silica. Then the prepared structure was functionalized with 3-chloropropyltrimethoxysilane molecule and then chlorine atom was replaced with 2-aminoterephthalic acid ligand. Then, in order to form an metal- organic framework on the prepared composite structure, copper metal salt was added to the ligand, and during the chemical reaction, a metal- organic framework based on copper(II) was formed on the magnetic composite structure. The prepared catalyst was used for the synthesis of amide compounds from aldehydes with electron withdrawing and electron donating groups and aromatic and aliphatic amines, and after the completion of the reaction, it was easily separated from the reaction by applying an external magnetic field. Also, the catalyst was studied and eva‎luated using various analyses, such as FT-IR, EDX, Fe-SEM, TGA, XRD and VSM. After optimizing the conditions, the reaction was carried out for 4 hours in the presence of the oxidant tert-butyl hydroperoxide and calcium carbonate base at a temperature of 80 °C in acetonitrile solvent, and various derivatives of amides were synthesized with an efficiency of 80-96%. Also, the catalyst showed the ability to be reused 7 times without significant reduction in product formation efficiency

آميد، الدهيد، آميد داركردن اكسايشي، چهار چوب فلزي– الي ، كاتاليزگر ناهمگن مغناطيسي

Amide, aldehyde, oxidative amidation, metal-organic framework, magnetic heterogeneous catalyst.

hossein salehi

ali maleki