مهتاب عباسي

This project investigates the neural mechanisms underlying hand movements in rhesus monkeys through two separate studies. The first study examines brain connectivity during voluntary bilateral hand movements in monkeys using the direct transfer function (DTF) method to assess effective connectivity in four frequency bands, delta, theta-alpha, beta, and gamma. This study analyzes the intra-regional and inter-regional connections in the motor cortex, ventral prefrontal cortex (VLPFC) and dorsolateral prefrontal cortex (DLPFC), and it reveals significant interactions between the motor cortex and prefrontal areas, especially the primary motor cortex (M1) and the ventral prefrontal cortex. These findings indicate a one-way connection from the motor cortex to the prefrontal cortex during right and left hand movements. The second study focuses on the dynamics of brain connectivity in different movement states of the contralateral hand, using phase-locked value (PLV) analysis to eva‎luate functional connectivity in the mentioned frequency bands. The results highlight the role of the delta band in enhancing neural coordination during movement execution, while the beta band is associated with motor preparation and the gamma band with increased neural activity during movement execution. These findings deepen our understanding of motor control mechanisms and have potential implications for the development of therapeutic strategies to address motor deficits.

پويايي ارتباطات مغزي , ارتباطات عملكردي , ارتباطات موثر , مقدار قفل فاز , تابع انتقال مستقيم

dynamic brain connectivity , functional connectivity , effective connectivity , phase locking value , directed transfer function

Mahtab Abbasi

Dr. Abbas Erfanian Omidvar