Preparation an‎d Characterization of a Magnetic Nanocatalyst Based on CuAl-LDH/Cu-MOF-74 an‎d Investigation of Catalytic Application in the Synthesis of Amide Derivatives from Alcohol

1/21/2027 12:00:00 AM

In this work, a novel heterogeneous magnetic nanocatalyst based on CuAl-LDH an‎d Cu-MOF-74 has been reported. This nanocatalyst were used for oxidative amidation from benzylic alcohols in the presence of amine hydrochloride salts. For this purpose, firstly magnetic nanoparticles were prepared as the central core an‎d then CuAl-LDH nano sheets were grown directly on the surface of these nanoparticles. Afterwards, the Cu-MOF-74 framework by using 2,5-dihedroxy terephthalic acid an‎d under solvothermal conditions was synthesized in situ on the copper centers in layer double hydroxide nanosheets. The prepared magnetic nanocatalyst structure was eva‎luated by using various techniques including infrared spectroscopy (FT-IR), x-ray diffraction (XRD), scanning electron microscopy (FE-SEM), specific surface area (BET) an‎d thermogravimetric analysis (TGA). The results of these analysis confirmed the successful formation of nanocomposites, suitable thermal stability an‎d porous structure with good surface area. The efficiency of catalyst prepared in oxidative amidation reaction of benzylic alcohols with amine hydrochloride salts in acetonitrile was investigated in the presence of TBHP as oxidant an‎d calcium carbonate. The amide derivatives were synthesized up to 92 % in optimum conditions an‎d these structures were confirmed by FT-IR an‎d 1H-NMR analysis. The results showed that synergy effects between Fe₃O₄, CuAl-LDH an‎d Cu-MOF-74 structures increased surface area, improved electron transfer, suitable stability an‎d essay magnetic separation of the catalyst, which makes these nanocomposites an efficient choice for synthesis of amide compounds.

آميد , كاتاليزگر ناهمگن , هيدروكسيد دولايه , چارچوب فلز-آلي , نانوذره مغناطيسي

Amide. , Heterogeneous catalyst , Layer double hydroxide , Metal-organic frameworks , Magnetic nanoparticles

Nazanin Nejatbakhsh

Dr. Ali Maleki