Imidazo[1,2-a]pyridine continues to attract considerable attention in medicinal chemistry due to its capacity to generate structurally rich derivatives with meaningful biological activity. Throughout this booklet, the fundamental features of this scaffold, its major synthetic routes, an‎d the key elements shaping its structure–activity relationships have been outlined. In addition, a range of established pharmacological applications was reviewed, together with current research trends seeking to refine an‎d expan‎d the therapeutic potential of this heterocyclic framework. Evidence from contemporary literature highlights that carefully examining how structural modifications influence biological outcomes is central to designing improved drug can‎didates. Notably, recent approaches emphasize sustainable synthetic methodologies that rely on renewable resources such as lignin, opening new possibilities for constructing novel imidazo[1,2-a]pyridine derivatives. These strategies underscore the promising future of this scaffold, which remains a fertile platform for developing innovative compounds with enhanced pharmacological performance.

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IMIDAZO[1,2-A]PYRIDINES SYNTHETIC PATHWAYS an‎d RECENT MEDICAL APPLICATIONS

1-تعيين ايميدازو[1،2-A]پيريدين‌ها , 2-روش‌هاي سنتز ايميدازو[1،2-a]پيريدين‌ها , 3-خواص فيزيكي و شيميايي ايميدازو[1،2-a]پيريدين‌ها , 4-كاربردهاي دارويي فعلي و بالقوه ايميدازوپيريدين‌ها , 5-كاربردهاي دارويي فعلي و بالقوه ايميدازو[1،2-a]پيريدين‌ها

1-Devination of IMIDAZO[1,2-A]PYRIDINES , 2- Synthesis Methods of Imidazo[1,2-a]pyridines , 3- Physical an‎d Chemical Properties of Imidazo[1,2-a]pyridines , 4- Current an‎d Potential Pharmacological Applications of Imidazopyridines , 5-Current an‎d Potential Pharmacological Applications of Imidazo[1,2-a]pyridines