16647

16647

سنتز مشتقات بنزايميدازولي با استفاده از نانو زيست كاتاليست ايزين گلس مغناطيسي

كارشناسي ارشد

نانو شيمي

اسفند 1394

دكتر شهرزاد جوانشير

دكتر محمد قربان دكامين

شيمي

طي دو دهه¬ اخير تلاش زيادي براي ارايه راهكار¬هاي مؤثر و كار¬آمد براي سنتز تركيبات آلي با به كارگيري واكنش¬هاي چندجزيي تحت شرايط دوستدار محيط زيست صورت گرفته است. از جمله تلاش¬هايي كه در اين زمينه صورت گرفته مي¬توان به انجام واكنش¬هاي چندجزيي با كارآيي اتمي بالا در شرايط بدون حلال و يا استفاده از آب و اتانول به عنوان حلال سبز، استفاده از كاتاليزورهاي قابل بازيافت و همچنين استفاده از روش-هايي جهت كاهش مصرف انرژي اشاره كرد. بنابراين لازم است كه مقدمه¬اي در ارتباط با اين زمينه¬ها بيان شود.

1395/11/26

7/14/2017 12:00:00 AM

Abstract In recent years the use of biodegradable polymers to develop green chemistry as a catalyst is increased day by day. However the weakness in some of the properties of the catalyst make scientists to use nano-size materials, such as magnetic nanoparticles. The benefits of this class of catalyst are: easy to separate from the reaction, recovery, substantially stable in organic solvents an​d reaction respectively. Isinglass is a material that comes from the swimming balloon of fish. Its structure is composed of collagen an​d contains a number of different amino acids. Due to the presence of amino an​d acid groups in isinglass, it acted as a two-factor catalyst, an​d leads the reaction. Other features of the catalyst can be pointed to the low price an​d availability. Benzimidazole one of the most important nitrogen-containing heterocyclic compounds due to its many biological an​d pharmacological activity has always been of interest to chemists an​d researchers. In this project the synthesis of various substituted derivatives of benzimidazole using magnetic nano-bio-catalyst isinglass. The proposed approach can be used to take advantage of easy high product purity, eco-friendly products as well as being noted.