چكيده به لاتين
Abstract:
Nowadays, green chemistry is dealing with healthy chemical reactions with the safe products and maximum yield (the minimum consumption of materials and energy), multicomponent reactions and nanocatalysts could lead us towards this goal. Imidazole, quinazolinone, and xanthene heterocyclic rings are at the core of many important commercial drugs. However, these components have not been studied extensively owing to one of the main reasons, i.e., synthesis limitation. Thus, in this research, first, the core/shell nanocatalysts as well as magnetic composite have been prepared and then used in the three synthetic reactions for the preparation of imidazole, quinazolinone, and xanthenes heterocyclic compounds. The recovery of catalysts from the reaction media found to be possible with ease and without complex separation processes, and have been used in other reactions many times. The use of recyclable bionanocatalysts without toxic transition metals and green solvents, simplicity of the method, short reaction time, high yield, low cost, and lower pollution could be mentioned amongst the advantages of this research. The identification and characterization of the prepared nanostructures and composites have been investigated utilizing Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction spectroscopy (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDAX), thermal gravimetric analysis (TGA), Brunauer–Emmett–Teller (BET) surface area and pore analysis, and vibrating sample magnetometer (VSM), to name but a few. In the end, products have been detected through the data investigation of infrared spectroscopy as well as proton and carbon nuclear magnetic resonance (NMR). In addition, it would be expected that these compounds show the significant medicinal and biological properties due to the structural similarity to known drugs.
Keywords: imidazole, quinazolinone, xanthene, recyclable catalyst, reactions multi-component, magnetic nanoparticles.
