چكيده به لاتين
In recent years, hyperthermia by magnetic fluid has become one of the most promising ways
to treat cancer, while using this mrthod has many challenges and deficiencies. One of thede
challenges is the lack of accurate and adequate information on how to disperse magnetic
nanoparticles anfter injection of the nanoparticles into a cancerous tumor. Therefor, the main
purpos of this thesis is to analyze the diffusion of nanoparticles in the tissue after injection and
the effect of various parameters such as injection rate and fluid concentration on it. In order to
achieve this goal, first, the color distribution as a similar fluid to the magnetic nano fluid, with
different concentration in the chicken breast tissue was investigated as a similar tissue to human
breast tissue and then the magnetic nanofluid was investigated. In the next step, by using image
processing techniques in MATLAB software, processing was performed on photos that taken
after nanoparticle injection and tissue cutting, and the result of these processing were analyzed
using COMSOL software, and finally a model for tissue heating after injection and doing
hyperthermia was optained. By using this model and the results obtaind in this thesis, it is
possible to accurately predict the outcome of the hyperthermia process befor doing its
experimental and clinical investigation at a much lower cost.
In this thesis, hyperthermia and heat generation methods were investigated in living tissue at
first, and then details of hyperthermia by using magnetic nanoparticles were investigated. In
the following the dispersion of nanoparticles after injection into the tissue and then the
distribution of temperature after hyperthermia have been investigated and examined.
Subsequently, the empirical results obtained from the experimental experiments on image
processing have been used to simulate hyperthermia by COMSOL sofware and its results have
been analyzed. Finally, it is also to summarize and submit suggestions for future works
