چكيده به لاتين
The most important compound in tobacco is nicotine, which is today the main cause of tobacco addiction and has been used as a pesticide in the past and is absorbed through the skin, nasal mucosa and mouth. Symptoms of nicotine include increased heart rate, increased blood pressure, increased blood lipids, seizures, and death. Due to the complexity of the actual sample tissue, the preparation stage of the sample is very important. In the present study, due to the high solubility of nicotine in aqueous media and the difficulty of isolating the environment, a microscopic microscopy/gas chromatography-mass spectrometer method was used for the extraction of nicotine with the use of novel polymers. The coating used is phenyltrimethoxy-silane wound, which was first synthesized by the chemical bonding method on silica fiber. One of the benefits of this coating is simple synthesis, thermal, mechanical, and high surface area. In order to achieve the best performance, the factors influencing the extraction process including temperature, pH, time and ionic strength were optimized using the design of the test using a central composite design. Under the optimum conditions, the repeatability and regeneration of the method were obtained 5.7% and 10.1%, respectively. Linear range was obtained in two intervals of 0.1-1000 and 1000-5000 ng/ml with a correlation coefficient of 0.9955 and 0.9975. The diagnostic limit and the determination limit were also equal to 0.02 and 0.08 ng/ml respectively. In the end, this method was successfully used for the extraction and measurement of nicotine in brackish water samples.
