احمدرضا جهانيان

Microfluidics is a rapidly evolving field that focuses on the use of minimal volumes of fluids, typically in the microliter or nanoliter range. This engineered miniaturization helps us perform many tests while reducing cost and time, more portability, and less space. Cervical cancer, which is the fourth most common cancer among women, affects about 500,000 new patients every year. The Pap smear test is the first step in identifying this cancer through observing the stained cell sample under the microscope, which has been able to control the spreading of this cancer. Considering the time-consuming nature of this test and the need for a laboratory operator to perform the test process, the need for a device to perform the test is an important issue. In this research, a platform has been designed and built for the Pap smear test, which is capable of staining the cell sample according to the laboratory protocol, eliminating the need for an operator to perform this test, and by automating this process, the pathologist is free from unnecessary laboratory routines. With the suggestion of a completely exclusive valve based on magnets and blades, the manufacturing and optimization steps were carried out and finally, the cell smeared on the coverslip was stained. The results were compared with the laboratory results and the pathologist considered the samples stained by the device suitable for eva‎luation to identify cancer cells.

ميكروسيالات , ميكروسيالات سانتريفيوژ , پاپ اسمير , سرطان دهانه رحم

microfluidics , centrifugal microfluidics , cervical cancer , pap smear

ahmad reza jahanian

dr. mahdi navidbakhsh and dr. esmail pishbin