چكيده به لاتين
Pharmaceutical products are essential factors in life. Pollution caused by this group is created through human consumption, Application in veterinary medicine, pharmaceutical industry, and agricultural industry, and household and hospital waste. It is necessary to remove pharmaceutical pollutants from the aquatic environment due to the harmful effects of these substances on the ecosystem. This study focused on the liquid-liquid extraction of Ibuprofen using Aliquat as an extractant and n-Hexane solvent in a serpentine microchannel with dimensions of 10 cm in length, 400 μm in width, and 300 μm in depth. And then, the extraction kinetics has been investigated in the serpentine channel. The serpentine channel, due to its distinctive structure, exhibits increased extraction efficiency attributed to enhanced mixing. The microchannel, initially constructed from glass, underwent an exploration of parameters including the initial concentration of ibuprofen (10-30 ppm), extractant concentration (2-10 mM), pH of the aqueous solution (3-11), and flow rate (1.0-1.5 mL/hr). Optimal conditions for extraction were determined, resulting in an Ibuprofen input concentration of 12 ppm, extractant concentration of 7 mM, pH=10, and a flow rate of 1.1 mL/hr, achieving an extraction efficiency of 98.5%. The investigation into the extraction kinetics of ibuprofen involved studying the extraction rate and removal of ibuprofen from the aqueous solution at different flow rates (0.8-2.2 mL/hr). The obtained data were fitted to various kinetic models, with all models demonstrating agreement with the kinetic data. Notably, the pseudo-second-order (linear) kinetic model performed the best, showing an R^2 value of 0.9997 and a kinetic rate constant of 0.027 (1/s.ppm).
