چكيده به لاتين
Chitosan is a hydrophilic polysaccharide derived from chitin. The main monomer of chitosan is N-glucosamine. Chitosan has important properties such as biocompatibility, non-toxicity, biodegradability, and its use in green chemistry has been considered as an excellent support for catalytic systems. The applications of chitosan can be mentioned in food, pharmaceutical, biomedical, scaffolding, etc.In general, chitosan is an ideal and versatile polysaccharide due to its inherent properties.
5-Sulfosalicylic acid is a triple aromatic compound that has undergone the usual reactions of phenol, carboxylic acid and sulfonic acid groups and is a common anti-inflammatory drug.The aim of this research in the first stage was to design and manufacture a nanocatalyst based on chitosan using 5-sulfosalicylic acid, which in the second stage was used as a catalyst for the synthesis of antihypertensive drug analogs of nifedipine through four-component Hanch and anti-M reactions. . SD methyl fumarate will be used.
